Theophylline is related chemically to the natural metabolite xanthine, which is a precursor of uric acid. The topic of Xanthine Medications will likely be covered in the Pharmacology courses of your school program. ... Bronchodilators: Beta-Agonists Mechanism of Action. How Do These Drugs Work? at present, three major classes of bronchodilators, β(2)-adrenoceptor (AR) agonists, muscarinic receptor antagonists, and xanthines are available and can be used individually or in combination. All content is free. It is the responsibility of the Respiratory Therapist to learn about the drug class. When administering the methylxanthine theophylline, the nurse can expect: A. Option D: Theophylline is a methylxanthine bronchodilator. Theophylline (dimethylxanthine) has been used to treat airway diseases for more than 80 years. The nurse instructs the client to limit the intake of xanthine-containing foods such as chocolate, cola, cocoa, tea, and coffee. The mechanisms of actions focus on relaxation, dilation and decrease in secretions. 19) • Prototype Drugs: – Theophylline-Theo-dur – Aminophylline . Begins at the specific receptor stimulated Cushley MJ, Holgate ST. Bronchodilator actions of xanthine derivatives administered by inhalation in asthma. Because of their methyl attachments, these agents are often referred to as methylxanthines. Bronchodilators: ü Xanthines Derivatives . Specific xanthine agents. 5. Read more about the prescription drug XANTHINE DERIVATIVES - ORAL. Indications are based on acute and chronic pulmonary disease and dysfunction. We also have a guide on Adrenergic Bronchodilators that I think you will enjoy. Study asthma - bronchodilator Xanthine drugs flashcards from georgie mair's bristol university class online, or in Brainscape's iPhone or Android app. Xanthine Derivatives (Refer to Prototype List in syllabus, pg. Bronchodilators work through their direct relaxation effect on airway smooth muscle cells. Figure 8-1 shows the general xanthine structure and the structures of theophylline (1,3-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine). Consumer information about the medication XANTHINE DERIVATIVES - ORAL , includes side effects, drug interactions, recommended dosages, and storage information. With bronchodilator types being B-agonists, anticholinergic and xanthine derivatives. The airway response to the inhalation of four alkyl xanthines was studied in 17 subjects with moderately severe asthma (mean FEV1 1.19 litres, 42% predicted). Bronchodilators Xanthine derivatives Beta-agonists Anticholinergics Antileukotriene agents Corticosteroids Mast cell stabilizers Sympathomimetic Agents ie epi, ephedrine, isoproterenol, terbutaline. The xanthine alkaloids—caffeine, theobromine, and theophylline—are closely related compounds found in a variety of plants indigenous to several continents. Decreased pulmonary function B. 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